Clustering des trajectoires thérapeutiques pour la bronchopneumopathie chronique obstructive (BPCO) : comparaison des méthodes d’encodage de séquences
Event: 17ème Colloque Données de Santé en Vie Réelle de l’AFCROs, Paris, France Authors: Romane Pean, Nina Temam, Diane Vincent, Marie Génin, Pauline Guilmin View Presentation Introduction L’analyse des séquences thérapeutiques et évènements médicauxest essentielle pour optimiser la prise en charge des patients. Cependant, lacomplexité et variabilité de ces séquences posent un défi méthodologique. Leclustering […]
Identification of risk profiles for liver injury in adults with multiple sclerosis using artificial intelligence method
Event: The Liver Meeting – AASLD (American Association for the Study of Liver Diseases) 2024, San Diego, California, USA Authors: Dominique Larrey, Fang Liz Zhou, Claire Brulle-Wohlhueter, Myriam Benamor, Jeffrey Chavin, Neda Razaz, Raphael Bejuit, Julien Dauriat, Théophile Reppelin, Romane Péan, Sam Ekhtiari, Nicolas Wagner, Fred Lublin View Poster Background The evolution of multiple sclerosis (MS) […]
Identification of risk profiles for liver injury in adults with multiple sclerosis using artificial intelligence method
Authors: Dominique Larrey, Fang Liz Zhou, Claire Brulle-Wohlhueter, Myriam Benamor, Jeffrey Chavin, Neda Razaz, Raphael Bejuit, Julien Dauriat, Théophile Reppelin, Romane Péan, Sam Ekhtiari, Nicolas Wagner, Fred Lublin Event: Congrès AFEF (Association Française pour l’Étude du Foie) View Poster Introduction et Objectif L’évolution du traitement de la sclérose en plaques (SEP) au cours des deux dernières […]
Cluster Algorithm for Credible Subgroup Identification in Patients with Erectile Dysfunction Receiving Tadalafil: A Real-World Data Study
Event: ISPOR Global 2023, Boston, MA, USA Authors: KT. McVary, C. Daluwatte, RA Kloner, M. Montmerle, M. Rollot, P. Guilmin, M. Blanchon, N. Lambert, C. Esnault, A. Stewart, T. McGraw View Poster Objectives: This non-comparative, retrospective study aimed to characterize the profiles of erectile disfunction (ED) patients prescribed with tadalafil by clustering the homogenous subpopulations with different […]
Cluster analysis of kidney function decline among males with Fabry disease in a large United States electronic health records database
Publisher: ndt (Nephrology Dialysis Transplantation)Authors: A. Chiorean, N. Lyn, S. Kabadi, M. Blanchon, P. Hayat, P. Loustalot, M. Maski, M. Montmerle, E. Ponce View publication Background Fabry disease (FD) is an X-linked lysosomal storage disorder caused by deficient α-galactosidase A activity. The spectrum of disease includes phenotypes ranging from ‘classic’ to ‘later-onset’, with varying kidney disease progression. Identifying patterns of declining kidney function […]
Identification of Predictive Factors of Diabetic Ketoacidosis in Type 1 Diabetes Using a Subgroup Discovery Algorithm
Publisher: Diabetes, Obesity and MetabolismAuthors: Angela Ibald-Mulli, Jochen Seufert, Julia M. Grimsmann, Markus Laimer, Peter Bramlage, Alexandre Civet, Margot Blanchon, Simon Gosset, Alexandre Templier, W. Dieter Paar, Fang Liz Zhou, Stefanie Lanzinger View publication Aim To identify predictive factors for diabetic ketoacidosis (DKA) by retrospective analysis of registry data and the use of a subgroup […]
Qluster: An easy-to-implement generic workflow for robust clustering of health data
Publisher: Frontiers in Artificial IntelligenceAuthors: C. Esnault, M. Rollot, P. Guilmin, J-D. Zucker View publication Background The exploration of heath data by clustering algorithms allows to better describe the populations of interest by seeking the sub-profiles that compose it. This therefore reinforces medical knowledge, whether it is about a disease or a targeted population in real life. Nevertheless, […]
Epidemiology, treatment patterns, clinical outcomes, and disease burden among patients with immune‐mediated thrombotic thrombocytopenic purpura in the United States
Publisher: Research and practice in thrombosis and haemostasis (rpth)Authors: A. Adeyemi, F. Razakariasa, A. Chiorean, R. de Passos Sousa View publication Background Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening thrombotic microangiopathy. Due to its rarity, epidemiology and real‐world outcomes data are scarce. Objectives The aim was to assess epidemiology, treatment patterns, clinical outcomes, and […]
Clustered analysis of Fabry disease progression in a large US electronic health records database (Optum Market Clarity): A retrospective observational cohort study
Event: WORLD Symposium 2022, San Diego, CA, USA Authors: A. Chiorean, S. Kabadi, P. Hayat, M. Montmerle, E. Ponce, M. Blanchon, N. Lyn, M. Maski View Poster Introduction: As the spectrum of Fabry phenotypes remains uncertain, the study objective was to describe patterns of progression in untreated Fabry disease (FD) patients from a large electronic […]
Assay Harmonization and Use of Biological Standards To Improve the Reproducibility of the Hemagglutination Inhibition Assay: a FLUCOP Collaborative Study
Publisher: ASM Journals / mSphereAuthors: J. Waldock, L. Zheng, E.J. Remarque, A. Civet, B. Hu, S. Lartey Jalloh, R. Jane Cox, S. Ho, K. Hoschler, T. Ollinger, C.M. Trombetta, O.G. Engelhardt, C.Caillet View publication Background The hemagglutination inhibition (HAI) assay is an established technique for assessing influenza immunity, through measurement of antihemagglutinin antibodies. Improved reproducibility of […]
