AI-Driven Disease and Care Modeling and Simulation: A Framework for Simulating Real-World Scenarios in Non-Small Cell Lung Cancer (NSCLC)
Event: ELCC 2025, Paris, France Authors: Antoine Movschin, Lise Bosquet, David Pérol, Melissa Rollot, Louise Dry, Coriande Clemente, Farah Al Nakib, Mathilde Berthelot, Margaux Törnqvist View Poster Background Advances in personalized medicine have driven targeted therapy for NSCLC through mutation identification, but their rarity in real-world (RW) settings limits traditional RCTs. External control arms (ECAs) offer an […]
Machine Learning (ML) applied to real-world data to guide prescription of immune-therapies in metastatic melanoma: a pilot study
Event: ISPOR Global 2023, Boston, MA, USA Authors: F. Gwadry-Sridhar, Billy Amzal View Poster Objectives: Newly diagnosed metastatic melanoma patients are often treated with molecular targeted therapy (TT) or with immunotherapy (IO). However, only a limited proportion of patients respond to those therapies, resulting in reduced survival and substantial inefficiencies for health systems. The purpose […]
Social deprivation aggravates post-operative morbidity in carcinologic colorectal surgery: Results of the COINCIDE multicenter study
Publisher: Journal of Visceral SurgeryAuthors: A. Alves, A. Civet, A. Laurent, Y. Parc, C. Penna, S. Msika, M. Hirsch, M. Pocard, G. Coincide View publication Aim of the study Evaluate the impact of social deprivation on morbidity and mortality in surgery for colorectal cancer. Methods The COINCIDE prospective cohort included nearly 2,000 consecutive patients operated on […]
A predictive model for risk of early grade ≥ 3 infection in patients with multiple myeloma not eligible for transplant: analysis of the FIRST trial
Publisher: Leukemia (Nature)Authors: C. Dumontet, C; Hulin, M.A. Dimopoulos, A. Belch, A. Dispenzieri, H. Ludwig, P. Rodon, J.V. Droogenbroeck, L. Qiu, M. Cavo, A.V. de Velde, J.J. Lahuerta, O. Allangba, J.H. Lee, E.Boyle, A. Perrot, P. Moreau, S. Manier, M. Attal, M. Roussel, M. Mohty, J.Y. Mary, A. Civet, B. Costa, A. Tinel, Y. Gaston-Mathé, T. Facon […]
MMS19 as a potential predictive marker of adjuvant chemotherapy benefit in resected non-small cell lung cancer
Publisher: Cancer BiomarkersAuthors: J. Adam, T. Sourisseau, K.A. Olaussen, A. Robin, C.Q. Zhu, A. Templier, A. Civet, P. Girard, V. Lazar, P. Validire, M. S. Tsao, J.-C. Soria, B. Besse View publication Background Resectable non-small cell lung cancer (NSCLC) treatment options most often consist of surgical resection along with adjuvant chemotherapy (ACT). The benefit of ACT however […]
