Cluster analysis of kidney function decline among males with Fabry disease in a large United States electronic health records database
Publisher: ndt (Nephrology Dialysis Transplantation)Authors: A. Chiorean, N. Lyn, S. Kabadi, M. Blanchon, P. Hayat, P. Loustalot, M. Maski, M. Montmerle, E. Ponce View publication Background Fabry disease (FD) is an X-linked lysosomal storage disorder caused by deficient α-galactosidase A activity. The spectrum of disease includes phenotypes ranging from ‘classic’ to ‘later-onset’, with varying kidney disease progression. Identifying patterns of declining kidney function […]
Qluster: An easy-to-implement generic workflow for robust clustering of health data
Publisher: Frontiers in Artificial IntelligenceAuthors: C. Esnault, M. Rollot, P. Guilmin, J-D. Zucker View publication Background The exploration of heath data by clustering algorithms allows to better describe the populations of interest by seeking the sub-profiles that compose it. This therefore reinforces medical knowledge, whether it is about a disease or a targeted population in real life. Nevertheless, […]
Compare renal function preservation outcome of SGLT2 Inhibitor vs. DPP4 Inhibitor in patients with type 2 diabetes: a retrospective cohort study of Japanese commercial database with advanced analytics approach
Event: ISPOR Europe 2018, Barcelona, Spain Authors: F.L. Zhou, H. Watada, Y. Tajima, M. Berthelot, D. Kang, C. Esnault, Y. Shuto, H. Maegawa, D. Koya View Poster Background Tofogliflozin, a highly selective sodium/glucose cotransporter 2 inhibitor (SGLT2i), was approved in Japan for Type 2 Diabetes Mellitus (T2DM) in May 2014. It is marketed as Apleway/Deberza, […]
