Hemolytic Markers, Mortality and Thromboembolic events in Cold Agglutinin Disease (CAD) with risk assessment by disease duration
Event: European Hematology Association (EHA) Congress 2023, Frankfurt, Germany Authors: Q.A. Hill, W. Barcellini, A. Röth, A. Karaouni, M. Afonso, R. Yoo, J. Tanniou, J. Rubio, C. Broome View Poster Background Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia (AIHA) characterized by classical complement pathway-mediated hemolysis. Although there is consensus on an increased […]
Machine Learning (ML) applied to real-world data to guide prescription of immune-therapies in metastatic melanoma: a pilot study
Event: ISPOR Global 2023, Boston, MA, USA Authors: F. Gwadry-Sridhar, Billy Amzal View Poster Objectives: Newly diagnosed metastatic melanoma patients are often treated with molecular targeted therapy (TT) or with immunotherapy (IO). However, only a limited proportion of patients respond to those therapies, resulting in reduced survival and substantial inefficiencies for health systems. The purpose […]
AI-Powered Pre-Competitive Disease and Care Modeling: Building a Reference Disease-Centric Framework for Value-Based Decision Making
Event: ISPOR 2023, Boston, MA, USA Authors: B. Amzal, A. Movschin, A. Chiorean,J. Tanniou, M. Rollot, M. Génin View Poster Objectives Drugs evaluation has been undergoing a transformational shift from the classical sequence of randomized control trials (RCT) and Real-World (RW) studies towards a more agile process, capitalizing better and faster from retrospective data. The purpose of this […]
Cluster Algorithm for Credible Subgroup Identification in Patients with Erectile Dysfunction Receiving Tadalafil: A Real-World Data Study
Event: ISPOR Global 2023, Boston, MA, USA Authors: KT. McVary, C. Daluwatte, RA Kloner, M. Montmerle, M. Rollot, P. Guilmin, M. Blanchon, N. Lambert, C. Esnault, A. Stewart, T. McGraw View Poster Objectives: This non-comparative, retrospective study aimed to characterize the profiles of erectile disfunction (ED) patients prescribed with tadalafil by clustering the homogenous subpopulations with different […]
A Natural Language Processing (NLP) Approach to Automate Patients’ Testimonials Analysis
Event: ISPOR Europe 2022, Vienna, Austria Authors: P. Hayat, C. Clémente, V. Martenot, M. Rollot View Poster Objectives: Patients’ testimonials (e.g. posts on forums or responses to questionnaires) provide valuable insights to define and characterize patient-reported outcomes (PRO), quality of life and patients’ perspective of disease symptoms. However, traditional NLP methods used for automated analysis of patients’ […]
Une nouvelle approche d’analyse automatique de réponses de questionnaires patients basée sur les modèles de langages
Event: 14ème colloque annuel des Données de Santé en Vie Réelle 2022, AFCROs, Paris, France Authors: L. Deplante, P. Hayat, M. Rollot View Poster Introduction Les questionnaires à réponse ouverte représentent un outil précieux de la recherche épidémiologique pour recueillir la perception des patients sur leur maladie, leur qualité de vie ou leur prise en charge, […]
Using Natural Language Processing (NLP) to understand self-reported barriers and enablers to treatment adherence in type 2 diabetes (T2D) using data from the International Diabetes Management Practices Study (IDMPS)
Publisher: ADA 2022, New Orleans, LA, USA Authors: J.C. Chan; J.J. Gagliardino; H.M. Ilkova; A. Ramachandran; J-C. Mbanya; M. V. Shestakova; M. Rollot; M. Blanchon; P. Hayat; J-M. Chantelot; P. Aschner View Poster Introduction IDMPS is an international, observational study to assess care practices and clinical profiles of people with diabetes in developing countries. […]
Identifying patients with Gaucher Disease type 3 (GD3) in the Optum’s de-identified Market Clarity database: a clustering analysis
Event: WORLD Symposium 2022, San Diego, CA, USA Authors: C. Rochmann, M. Génin, M. Blanchon, N. Lambert, L. Deplante, W. Heine, S.Kabadi View Poster Objectives GD3 is a progressive, Lysosomal Storage Disorder (LSD), distinguished from GD1 by early heterogenous neurological manifestations. Neurological presentation in GD1 patients is not well understood. Differentiation of GD3 from GD1 […]
Clustered analysis of Fabry disease progression in a large US electronic health records database (Optum Market Clarity): A retrospective observational cohort study
Event: WORLD Symposium 2022, San Diego, CA, USA Authors: A. Chiorean, S. Kabadi, P. Hayat, M. Montmerle, E. Ponce, M. Blanchon, N. Lyn, M. Maski View Poster Introduction: As the spectrum of Fabry phenotypes remains uncertain, the study objective was to describe patterns of progression in untreated Fabry disease (FD) patients from a large electronic […]
Unmet medical needs in people with type 2 diabetes treated by insulin: results from the International Diabetes Management Practices Survey (IDMPS)
Event: EASD (European Association for the Study of Diabetes) Annual Meeting 2019, Barcelona, SpainAuthors: A. Ramachandran, JC. Mbanya, P. Aschner, JJ. Gagliardino, H. Ilkova, F. Lavalle, M; Shestakova, J-M. Chantelot, A. Shaunik, A. Alvarez, M. Rollot, J. CN Chan View Poster Background and aims Limited data exist on the impact of different insulin therapy regimes on […]
